Showing posts with label Blood. Show all posts
Showing posts with label Blood. Show all posts

Wednesday, September 04, 2013

Patients with "Bad" Veins Can Prepare in Advance for IV Starts or Blood Draws

          Frequently I have cared for patients with challenging veins.  I prefer to call them "challenging," rather than "bad."  No one wants to be poked and prodded to have their blood drawn or have their IV therapy initiated.  It can be both painful and scary, as a patient, being advised that your veins are "bad" can actually be taken as an insult.  The patient may just feel that the nurse is "bad" at doing the sticking.  To  me, psychologically, it's better to begin with the right terminology to put the patient at ease.



          I have some techniques that have allowed me to have an extremely high rate of IV start success with challenging patients, but as a patient--there are some things that you can also do.  Here is my advice . . .

1.  Push fluids 24 hours prior to your blood draw or IV therapy.  Of course this is not always possible.  But many patients DO know that they will be needing a blood draw or a scheduled infusion on a regular basis. In such cases, really pushing oral fluids the day prior to the IV stick will make a difference.  UNLESS you are on fluid restriction, for some reason, try to take in at least three full glasses of water the day prior.  That extra fluid can make a wonderful difference in plumping up challenging veins.

2.  "Dangle" your hand or arm prior to the IV stick.  Gravity is your friend when it comes to dangling your hand or arm.  Instead of sitting with your hand or arm on the armrest or your lap, if you lower your arm straight down at the side of your chair while waiting for the nurse or technician to assemble the equipment, your veins in that extremity will be a bit plumper, due to gravity pooling some of your blood there.  This can really help.

3.  Apply heat to your veins. Nurses and phlebotomists know that heat applied to the skin above the vein will dilate the vein, making it plump up with blood and helping you have an easier stick.  However, you can't rely on a heating pad or any such helpful device actually being available to the staff.  (I have seen some really creative ways of trying to "make" some applied heat--not always a safe thing to do).  What you can do as a patient is use a hot water bottle that you have prefilled at home--keep it applied to your typically "best" veins to encourage a successful experience.  As an infusion nurse, I always had a heating pad tucked away for a particular patient--or on a day when the weather was so cold that "everyone" seemed to have hiding veins.  Again, that is not something you as a patient can depend on . . . Do ask if there is a blanket warmer available wherever you happen to be (ER usually has those)--wrap a pre-warmed blanket around the arm, and you can get some very good results.

4.  Suggest a vein, but allow your nurse to give a professional opinion.   When I get blood drawn, I usually point and say, "Right there."  But I have great veins, so no problem.  When an experienced provider starts looking at your veins, they make pretty quick judgments about where to go for the IV stick.  I have had situations where I've made my decision and have my needle poised, only to have the patient pipe up with, "You'll never get it there, no one ever does."  Well, actually I may well get it there, but I want every patient to have the right to tell me what works for them--but I'd prefer they tell me right up front.  

5.  Just breathe.  Some patients are better than others about relaxing during their venipuncture.  Some patients go so stiff and tense when the needle touches their skin, that it feels as if their arm has turned to stone.  When very anxious, doing some deep cleansing breaths (getting oxygen to the brain) can only help.  The easiest way to to this is breathe slowly and steadily IN through the nose for a count of 5 and then slowly releasing the breath--on another count of 5.  

6.  Be cautious with the IV.   It seems ridiculous to have to recommend caution, but I have seem some patients who have a hard time with the IV start, soon after start rummaging through their purse and dislodge the catheter!!  Please, don't be that person.  I'm not suggesting you sit completely still--just suggesting that you are extra careful for the duration of your infusion.

Later I'll post some of my favorite tips for the nurse starting an IV on a patient with challenging veins.

If you have a tip to share for patients with difficult veins--please feel free to share that in the comments section below.











Tuesday, December 01, 2009

A patient with Down's Syndrome and ARDS; Carol was not "my" patient

Not My Patient . . .

“Your patient is being discharged,” my nursing instructor informed me as we started our clinical rotation on a medical/surgical floor in my first year of nursing school.

"Oh, just great," I thought to myself.  I had spent hours learning about and planning the proper care for "my patient" who had recently suffered a basilar skull fracture.  My sheaf of clinical documents, medication lists, and a large pathophysiology flow sheet, were now suddenly made obsolete by my patient's imminent departure to a rehabilitation facility.

“He’ll still be here for a couple of hours. We’ll find you another patient later,” she assured me.

I was relieved that my painstakingly-crafted flow sheet, care plan, and medication cards wouldn’t go to waste. Although I only had one patient, the preparation required for the clinical day was nevertheless tedious and often proved exhausting in addition to other demands of family, school, and life in general.  Still, as a new nursing student with little experience in the healthcare setting, the advance preparation gave me confidence that I would know what to do for my assigned patient.  I decided not to fret about it, and simply hoped I'd be able to cope with whatever came my way in the shift ahead.

Our group of 10 nursing students and our instructor assembled at the nursing desk waiting for the nurses going off duty to give change of shift report to the group coming on.  We were working second shift, 3 pm to 11 pm that day.  Each week we spent three days attending lectures at our nursing college and two days working in the hospital to practice the hands-on-nursing skills and put into practice what we learned in class.  There was always a sense of heightened anxiety on our hospital days, particularly in the chaotic environment of our very large county hospital. This was a trauma center and the busiest hospital on the U.S. side of the Mexican border. It was also a teaching hospital, with a slew of resident doctors and interns managing most of the patient care. 

“The patient in 410 has a fever of 101.5!” a nursing assistant called out as she passed the nurses’ station where the harried day-shift nurse was “reporting off” to the oncoming "real" evening nurse and our huddle of nursing students.

The nurse going off shift sighed, “I’ll call the doctor—the girl in 410 just transferred here from the pediatric floor a half-hour ago. She’s supposed to go to the OR for surgery, an ORIF of the femur, as soon as her mom gets here to sign the consent.” The RN turned to our instructor, “It would help me out if one of your students could give her an acetaminophen suppository for the fever.”

Although none of our group was assigned to care for this new arrival to the surgical floor, we were always ready to perform a clinical skill to check off our list.  Therefore, an entourage of three students and our instructor entered room 410 where 18-year-old Carol, afflicted with Down's Syndrome and a fractured femur, would prove to teach me more than any other patient that day.

Carol had been struck by a car as she crossed a busy street the day before.  The fractured leg was her only known injury. She appeared to be sleeping deeply, with regular, but deep and fast respirations. Her eyelids fluttered as I explained that we needed to give her a suppository. Working together, we students gently repositioned her, mindful of the Buck's traction supporting her injured leg. A slight groan was Carol’s only acknowledgement as we cleaned her bottom (she had been incontinent with a bowel movement), before I inserted the suppository. Our instructor pointed out scattered petechiae on Carol's chest as we snapped a fresh gown across her hot skin and turned her to replace the soiled linen on her bed with clean sheets.

“These petechiae are probably the result of the trauma from her car accident,” our instructor explained, as she gestured towards the splash of flat pink spots that looked to me like tiny red freckles.

Back at the nurses' station our little group reassembled to continue shift report.  We told the nurse about our interventions and reported Carol's limited response to our actions.

“They gave her an injection of Demerol before she was transferred from the pediatric unit," the nurse mused, "And we don’t know her baseline mental status, she has Down's, and for all we know she could be profoundly retarded.” 

I was absorbed in my clinical experience for a few hours. The care for my basilar skull fracture patient proved to be very minimal. One of our nursing students needed a helping hand with a very complicated dressing change for a young man who had lost a leg in while trying to jump aboard a moving train.  And I was pleased to learn that another patient needed a new intravenous needle placed.  I was lucky enough to get the chance to do the venipuncture.  I suspect that I caused that patient a great deal of pain with my novice attempt, but with a seasoned nurse over my shoulder talking me through it, the result was satisfactory.  I kept busy in this way helping the staff nurses and other nursing students with their tasks until my patient was officially discharged.  My instructor disappointed me then by suggesting that I return to Carol and follow up on her care. It seemed a puzzling assignment to me, I knew there were no meds to pass, IV's to start or dressings to change in that room--and I was here to learn nursing . . . 

In Carol’s room I found that her mother had arrived from out-of-state.  She was regarding her daughter pensively.

“She won’t wake up,” she complained.

I repeated the explanation that the nurse had given us in report earlier, that Carol had been medicated with Demerol.

“When did they give that?  And how long will it last? Something’s just not right,” she continued.

Her questions were good ones.  I set out to find the "real" nurse to explain the mother's concerns, but the nurse arrived at that moment with a syringe in hand to give Carol another intramuscular injection of Demerol for her pain.  The busy nurse briefly attempted to reassure Carol's mother before rushing back to care for her other nine patients.

As I continued to converse with Carol’s worried mother, I became uneasy. She described a high-functioning independent young woman who lived in a group home while attending a vocational educational program in the city.  Demerol or not, the Carol we were observing didn't fit the girl her mother described.

Carol occasionally writhed and moaned, seeming to struggle to wake as her mother tried to arouse her. Her breathing was audibly harsh with a frequent moist cough.  The family doctor was alarmed at her appearance when he made informal rounds to check on Carol.  He wasn't in charge of her hospital care which was in the hands of the attending physicians who were on staff at this hospital, but he asked that the chief trauma resident be called to see her right away.

Before the staff nurse could return to Carol's room, the senior trauma resident appeared at the bedside and started questioning me.  He examined Carol while I slipped out to get her nurse who told me she would "be there as soon as she could."

Awkwardly, I waited with Carol's mother as the resident considered Carol.  He wondered aloud why she hadn't gone down to the OR earlier as scheduled. I reminded him of the fever and as he listened to her lungs, I casually pointed out the petechiae, which was more diffuse across her chest now.

The resident was suddenly abrupt and to the point, it seemed he'd slapped the last piece into a puzzle. “She’s thrown a fat embolus from her fractured femur--get her to ICU stat.” Then he turned on his heel and was gone before I could say a word.

I had enough of the classroom experience in nursing to fear a pulmonary embolism (a tiny blood clot that lodges in the lungs), but I didn't have a great deal of insight into the prognosis and treatment for a fat embolus. The hours that Carol's condition had progressed undetected were haunting me.  Right away I knew that Carol needed her nurse, and I needed my instructor.

It took some time to find Carol’s nurse and convince her that the resident wanted her patient transferred to ICU.  She made the requisite phone calls to confirm the orders and set the wheels in motion so that the ICU would assign Carol a bed.  Meanwhile, Carol's chart was nowhere to be found.  It was misplaced somewhere on the surgical floor.  I nervously looked for the chart while the nurse arranged for Carol's transfer.

My instructor, aware of the unfolding drama, gave me a brief suggestion, "Just help where you can with the transfer." 

Carol's mother, numb with worry, was making phone calls to advise her family members of this turn of events.  A sense of urgency was consuming me as I returned to Carol’s room. Carol's nurse was still on the phone making arrangements for the transfer. Suddenly the resident reappeared and scolded me. “This patient should have been in ICU already! Get her there now!!”

But no such luck . . .  The nursing unit had their own procedures to follow.  They set about taking a complete set of vital signs, "It's required that we do so before transferring a patient." 

The nurse's aide who was trying to check Carol's blood pressure was having a hard time because, "This machine can't be right, her pressure's way too low." She went to search for a manual blood pressure cuff that affirmed the hypotensive state of the patient.

Carol’s nurse returned with a respiratory therapist who placed a pulse oximeter on Carol's cool, pale finger and advised, “She needs oxygen, her oxygen saturation is only 65%!”  Her saturation should have been at least 92.  The oxygen set-up for transport through the hospital to the ICU floor would have to wait for a few minutes while someone went looking for the missing key to the metal portable oxygen cylinder. The precious moments SLOWLY passed as these tasks to make Carol ready for transfer were completed.

I felt useless as the evening nurse and an aide prepared the bed for transport. “What can I do to help?” I pleaded. 

“You can carry the patient’s bag of belongings and make sure not to bring her flowers, she can't have them in ICU,” the staff involved in this whole situation seemed snappy and angry.  I thought it was a waste of brain cells for the nurse in charge to even think about the flowers under the circumstances. In retrospect, I'm sure I was sensing the staff's anxiety and concern, and I have to believe they all shared my frustration with the obstacles that slowed the transfer to what seemed like a crawl.  

My neck flushed as we awkwardly maneuvered the Carol's bulky hospital bed into the hall and then, after all the delays, ironically took off running for the elevator leading to the intensive care unit. There wasn't enough room for all of us on the elevator.  Carol's mother and I rode together on an adjacent elevator.

The small ICU waiting room was overflowing with visitors waiting to be allowed in to see other patients. I said farewell to Carol's mother and urged her to call her ex-husband to let him know what was happening.

I'd never before been through the sliding doors that isolated the large intensive care unit from the rest of the hospital. No matter, I found Carol’s room easily. Nearly every nurse in the ICU was at her bedside, hooking up monitors, taking vital signs, putting in an additional IV, preparing suction, and hanging fluids.  I could see the resident doctor with his interns assembling supplies.  In a few minutes time Carol would have a tube in her trachea that allowed a mechanical ventilator to breathe for her. 

I layed down Carol's bag of belongings lingered in the background for a few minutes. Clearly Carol was in good hands, these nurses were calm and in control of the situation. 

Suddenly my shift was over--it was time to meet my instructor and the rest of the clinical group before going home.  But I was sad and miserable.  I went beyond my required textbook reading that night. Fat emboli and acute respiratory distress syndrome (ARDS) consumed my thoughts. I grieved for Carol's mother and lamented that I hadn't known enough to help expedite her care that evening.

Two days later as I skimmed the morning paper, I was shocked--but not surprised--to see Carol’s photograph smiling brightly from the obituary column.  I cut that little clipping out of the newspaper and pasted it into my tiny notebook of nursing tips.  To this day I still carry that notebook in my nursing work bag.  I guess Carol's legacy has been with me every day that I've worked as a nurse, now that I think of it.

Technically, Carol was never "really" my patient.  No medication cards, flow sheets, or care plan followed me to her room that evening and my education and experience to that point certainly didn't prepare me for the gravity of her situation.  Of course, ironically, it was the deepest and most vivid clinical situation I experienced as a student. I always recognized that I contributed little, but benefited much from this experience.  Many of the lessons learned are so obvious that they don't bear repeating.  

An obvious lesson that does bear repeating, on the other hand:  never assume nor underestimate any patient's baseline mental capacity.  Good communication with a responsible party who can provide definite information on a patient's usual abilities is absolutely vital so that care is not compromised or delayed in the event of important neurological changes.  That's Carol's legacy to me.




All rights reserved 2009 Carolyn Cooper MPH RN

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DVT, Blood Clot, Deep Vein Thrombosis



Dangerous blood clots may develop unexpectedly within the deep veins of a lower leg.  Such clots can cause deadly complications when microscopic pieces break off and clog the circulation to distant parts of the body.  Clots that find their way into the brain, lungs, or heart may result in deadly or life-altering complications from stroke,  pulmonary embolus, or heart attack. 

Preventing a DVT is certainly much easier than curing the condition.  In hospitalized patients several methods are used to enhance the flow of blood to the lower legs.  First and foremost, being up and around as soon as possible, and as much as possible after surgery or while recovering from an illness is a major advantage in increasing venous flow and decreasing the chance of clots forming.  Tight white compression stockings (TED hose) may be prescribed depending on the level of risk for the specific patient (see below).  Mechanical "pumps" squeeze the lower legs at regular intervals in another means of prevention.  For patients at the highest risk of DVT, blood thinning medication is injected daily under the skin of the abdomen.   

Greater Risk of Clots for Some Patients

DVT (Deep Vein Thrombosis) can occur in almost anyone. However, certain individuals may be at increased risk for developing a DVT. Risk factors include but are not limited to:
  • Recent surgical procedure (and greater chance of a DVT with a long, intense surgery and joint replacement surgeries)
  • Restricted mobility from bedrest, paralysis, traveling for many hours without taking a break to walk around
  • Active Cancer
  • Congestive Heart Failure (CHF)--if you take "water pills" and are not sure why--ask your doctor if you have CHF
  • Age greater than 40 years old
  • Pregnancy and the postpartum period (6-8 weeks after delivery)
  • Injury to the leg or the deep veins of the leg
  • Smoking
  • Use of certain medications such as birth control pills and estrogen
  • Dehydration
  • Polycythemia
  • Obesity
  • Current smoker
  • Past history of having a blood clot or an inherited family tendency to develop blood clots  
Spot a Clot  . . . a Campaign sponsored by the Venous Disease Coalition

Check out their website to learn more about DVT and related conditions such as:
  • Post Thrombotic Syndrome (PTS) After a DVT is treated and resolved, this chronic condition may result in up to 40% of all individuals.  It's the result of damage done by the clot to the valves that move blood through the vein.
  • Pulmonary Embolis (PE)  Blood clots in the smallest vessels of the lungs.
  • Thrombophila Blood that clots too easily. Hypercoagulability is another word used to describe this condition which can be inherited.
  • Chronic Venous Insufficiency results when the valves in the veins that move blood don't function properly, often occurs from injury to veins caused by a DVT, from varicose veins, or as the result of an inherited condition.
Venous Disease Coalition Patient Education Resources:

The Vascular Disease Foundation has a variety of full-color brochures available for download including a great pamphlet called "Focus on Clots."  (This publication was previously called "Spot a Clot," but otherwise it's the exact same informational card.)
You may also request a copy of these brochures by calling toll free: 1-888-833-4463.

Other related publications you can download:

Provided by the
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Tuesday, November 24, 2009

Another Black Box: Aranesp, Epogen, Procrit, What you should know about drugs that tell your body to make more red blood cells

Erythropoiesis Stimulating Agents (ESAs) tell your body to make more red blood cells. Drugs in this class include:

• Aranesp (darbopoetin alfa)
• Epogen (epoetin alfa)
• Procrit (epoetin alfa)
• There are other brand names & epoetin variants marketed worldwide

The Good News First . . .

Twenty years ago we didn’t have synthetic medications to treat anemia. Depending on the cause anemia was often treated through diet, by administering supplementary iron or vitamin B12, and frequently, by blood transfusions. The 1980's was a decade of concern over the safety of our blood supply due to blood borne pathogens such as Hepatitis B and C and the HIV virus. New technologies in recombinant DNA allowed science to explore and develop innovative alternative therapies.

In 1989, Epogen (epoetin alfa), the first of a class of drugs called erythropoiesis stimulating agents (abbreviated as “ESAs”), was approved by the FDA in the United States to treat patients suffering from anemia due to chronic kidney disease. Epogen was eventually joined by similar ESAs called Aranesp and Procrit and treatment was eventually broadened to include patients suffering from anemia related to chemotherapy.

The benefit to both groups was that they no longer needed to rely on frequent blood transfusions to treat their anemia. ESAs directly influence the body to speed up the production of its own red blood cells by introducing a synthetic version of the hormone erythropoietin. Erythropoietin is a chemical messenger of sorts with the specific mission of instructing our bone marrow to produce more red blood cells. Epogen, Aransep, and Procrit are easily given by a simple injection under the skin from one to three times per week.

So what exactly is anemia? Anemia results when we don’t have enough healthy red blood cells called erythrocytes circulating in our bloodstream. Healthy red blood cells are vital; they carry a protein called hemoglobin which picks up molecules of oxygen from our lungs and delivers it to the tissues throughout our body. We don’t store oxygen in our body but we use it continuously, and our body’s demand for oxygen is constant as oxygen molecules literally fuel every basic function that each cell in our body must perform.

Symptoms of Anemia. Moderate to severe anemia can cause symptoms of weakness, fatigue, shortness of breath, rapid/irregular heartbeat and pale skin. Milder or chronic anemia may cause subtle symptoms or no symptoms at all.

Erythropoietin. This hormone is a chemical messenger with several functions relating to the manufacture of red blood cells, preserving their lifespan in the body, and enhancing the growth of blood vessels. As we develop before birth, erythropoietin is active within our livers. After we are born, erythropoietin is manufactured and released by cells in the kidney.

Kidneys and Anemia. People often don’t think of a relationship between the kidneys and anemia, but when you carefully consider it, it makes sense for the kidney to have this function. Like a waste-water treatment plant adds chemicals based on the scientific observations of the plant technicians, the kidneys have specialized cells that detect decreased oxygen levels in the blood circulating through them, and as a result, these specialized cells release erythropoietin to enhance red blood cell formation and longevity. If the kidneys become diseased and fail, this system of checks and balances is impaired or lost. When ESAs, or synthetic erythropoietin, was first introduced in 1989, the drug was intended specifically for the benefit of patients in kidney failure.

Chemotherapy and Anemia. Cancer cells are bizarre mutant cells that divide rapidly. therefore, malignant tumors can grow large very quickly. The goal of chemotherapy is to target those rapidly-dividing bizarre cells and kill them. Other “good” rapidly-dividing cells in our body get caught in the cross-fire and are also damaged by chemo drugs. Hair is lost when rapidly-dividing cells in the roots are targeted by the chemo drugs. Other fast-growing cells affected by chemotherapy are in the digestive tract; that’s why mouth sores, nausea, and vomiting are a common consequence of chemo. The body’s rapidly dividing blood cells (red cells, white cells, and platelets) are also among the good cells that fall prey to chemotherapy. The anemia that results from chemotherapy is not caused by a lack of erythropoietin, but ESAs were approved by the FDA in 1993 to treat anemia to reduce the amount of blood transfusions necessary for patients suffering from chemotherapy-induced anemia.

Sobering News about ESAs . . .

All medications have both benefits and risks. In the U.S. the FDA places "black box warnings" on the medication labels and inserts of drugs when research suggests there is a risk of serious adverse effects. The first black box warning for ESAs appeared in March of 2007. Eight months later in November 2007, the black box warning was emphatically strengthened by the FDA.

Both the chronic renal failure and chemotherapy patients were found to have some increased risks when using ESAs. Patients with certain types of cancer were found to be at risks of tumor progression and decreased survival when taking ESAs to increase red blood cell production. Chronic renal failure patients were found to be at increased risk of developing heart attack, stroke, blood clots, heart failure and death if their ESA dose was high enough to cause them to make more than recommended number of red blood cells.

The FDA’s guidance to physicians was very specific on the recommended dosage to achieve good results without increasing patients’ risks for a bad outcome. Further, their guidance suggested that physicians specifically discuss the risks and benefits of these medications with their patients.

What’s Inside the Black Box . . . guidance for physicians about prescribing:

For patients with cancer: ESAs should only be used to treat anemia caused by chemotherapy—not to treat anemia from any other cause. After chemotherapy is finished, ESAs should no longer be used. Risks of tumor progression and decreased survival were noted in some clinical trials. The FDA strongly recommends that healthcare professionals discuss these risks with their patients before this therapy is started.

For anemic patients with chronic renal failure: Treat with the lowest level of the drug which will maintain hemoglobin levels within the target range of less than 12 g/dL. The established goal for this group is to maintain hemoglobin between 10-12 g/dL, because the risk for death and serious cardiovascular events increases when higher hemoglobin levels are achieved on ESA therapy. Further, it’s recommended that ESA therapy be discontinued if the patient’s hemoglobin levels remain so low that blood transfusions are still required.

What the FDA recommends for physicians and other healthcare professionals to discuss with their patients:

1. The primary goal of treatment with erythropoiesis stimulating agents (ESA) is to increase the number of red blood cells in order to avoid receiving blood transfusions.
2. These medications require at least two weeks of treatment before there is an increase in the number of red blood cells, and the dose may be adjusted periodically, but not more often than every four weeks.
3. ESAs increase the patient’s chance of blood clots and the risk of dying may be greater in certain circumstances.
4. Patients should keep appointments for blood tests so hemoglobin levels can be monitored.
5. Patients should monitor their blood pressure and call their healthcare provider for changes outside of the range that has been established for them.
6. Call the healthcare provider if they experience any of the following symptoms:
  • Pain and/or swelling in the legs
  • Worsening in shortness of breath
  • Increases in blood pressure
  • Dizziness or loss of consciousness
  • Extreme tiredness
  • Blood clots in hemodialysis vascular access ports

What the FDA wants patients to know about treatment with Aranesp, Epogen and Procrit . . .

Patients with cancer who are currently using or considering the use of an ESA should know the following:
• ESAs may shorten your survival time or may cause your tumors to grow faster.
• ESAs should only be used to treat anemia caused by chemotherapy and not other anemia from other causes in patients with cancer
• ESAs should not be used to treat the symptoms of anemia, such as fatigue or improve the quality of life in patients with cancer. The goal of treatment with ESAs is to avoid blood transfusions
• Treatment with an ESA should be stopped after you complete your course of chemotherapy.

Patients with chronic kidney failure (this includes both patients on dialysis and those not on dialysis) who are currently using an ESA should know the following:
• Your hemoglobin level should be checked regularly to make sure it stays between 10 and 12 g/dL.
• ESAs can increase your chance of heart attack, stroke, blood clots, heart failure, and death when they are given to maintain higher hemoglobin levels.
• If you are not responding to treatment with an ESA (your hemoglobin levels are not increasing) ask your doctor if you need to be checked for other causes of anemia.

Report Adverse Reactions to the FDA: Healthcare professionals are to report adverse and unexpected reactions with these meds to the FDA MedWatch reporting program online or by phone: 1-800-332-1088.

Links to more information about ESAs:

• Comprehensive information about ESAs from the U.S. Centers for Medicaid and Medicare Services: www.cms.hhs.gov/determinationprocess/downloads/id203d.pdf
• Kidney Disease and Anemia: http://kidney.niddk.nih.gov/kudiseases/pubs/anemia/
• Anemia and Kidney Disease: http://www.aakp.org/aakp-library/Anemia-in-Chronic-Kidney-Disease/
• A plus: Anemia and Kidney Disease from Anemia.org: http://www.anemia.org/patients/information-handouts/kidney-disease/
• ESA use for anemia in cancer patients: http://www.medscape.com/viewarticle/571464




.(All rights reserved, Carolyn Cooper, MPH, RN, 2009)  .. . .