Showing posts with label Infection. Show all posts
Showing posts with label Infection. Show all posts

Monday, June 07, 2010

Which Vaccines are Live?

(12/18/20:  Sorry for the typos, I will try to update this chart soon.)



 Sources of Information for Vaccines:

• Vaccine Information Statements (VIS): Available in many languages.
• CDC Vaccine Information Statements: Available in an audio version and in Spanish
• National Vaccine Information Center
• National Network for Immunization Information











Friday, January 22, 2010

Risk Factors for Deep Vein Thrombosis (DTV) and Venous Thromboembolism (VTE)

I've written about blood clots before on my blog, see DVT, blood clot, deep vein thrombosis.  I wanted to touch on this subject again because I came across a flyer from a class I once attended which introduced nurses to an excellent tool aimed at reducing the incidence of DVT by recognizing the individuals at greatest risk.  Patients need to know about this, too, so they can be vigilent and take precautions when they are at risk.

Apparently this educational endeavor is defunct because I cannot find a word about it in my Google searching.  "SCORE IT" DVT Patient Profiler for Selected Patients at Risk was presented by CARE FORCE (Clot Assessment & Risk Reduction Through Education).  The acronym SCORE IT cues the nurse to remember what patient types are at greater risk.  The more catagories that apply to a specific patient, the greater the risk and the need for higher levels of DVT prevention protocols in the hospital to be implemented in order to prevent a blood clot from developing.

I found this program compelling and want to record the information here for reference:

S . . . Surgery Patients.
    • General Anesthesia is a risk factor for postsurgical DVT development.
    • All surgeries are associated with risk of DVT/General and orthopedic surgeries are associated with a higher risk of developing DVT and PE (pulmonary embolus) than other types of surgery.
    • Total knee or hip replacement and hip fracture orthopedic procedures are associated with the highest postsurgical (within 1 to 2 weeks) risk of DV--over 50%.
C . . . Cancer Patients and Cardiovascular Patients
  • Cancer Patients
    • Chemotherapy, radiotherapy, central venous catheters, and surgery contribute to the increased risk of VTE (venous thromboembolism) in patients with cancer.
    • Tamoxifen or hormone replacement therapy are risk factors for DVT
    • Tumors may also cause obstruction which can contribute to venous stasis.
  • Cardiovascular Patients
    • Acute myocardial infarction (AMI), ischemic and non-ischemic cardiomyopahy, congestive heart failure (CHF) secondary to valvular disease, and chronic idiopathic dilated cardiomyopathy may increase the risk.
O . . . Obese Patients 
    • Modifiable Risk Factor
    • Weight loss may decrease risk
R . . . Respiratory Failure Patients
    • Acute exacerbation of chronic obstructive pulmonary disease (COPD), adult respiratory distress syndrome, moderate to severe community-acquired or nosocomial pneumonia, lung cancer, interstitial lung disease, or pulmonary hypertension are associated with increased risk.
E . . . Elderly Patients
    • Bed rest, frailty, and immobility features often associated with advanced age, predispose patients to venous stasis.
    • Advancing age (older than 40 years) is a risk factor for VTE.
    • As the population ages, the number of cases of VTE is expected to increase.
I . . . Infection/Inflammatory Disorder/Immobile/ICU Patients
  • Infection Patients
    • Disseminated infections, sepsis, and serious systemic infections, including urinary tract (UTI), complicated skin and skin structure, pneumonia, and abdominal infections may lead to increased risk of DVT.
  • Inflammatory Disorder Patients
    • Disorders such as systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD) are associated with an increased risk of IBD.
  • Immobile/ICU Patients
    • Venous stasis of the lower limbs may predispose a patient to thrombosis formation
    • Patients confined to bedrest for fewer than 5 days had a 21% occurrence of VTE compared to a 36% occurrence in patients on bedrest for over 10 days.  [There is no source citation given for these statistics on the flyer.]
    • Incidence of DVT in stroke patients with a paralyzed lower limb exceeds 50%. [No source cited.]
    • Increased risk in ICU patients with medical disorders.
T . . . Trauma/Thrombophila/Thromboembolism History Patients
  • Trauma Patients
    • Patients with major trauma who do not receive thromboprophylaxis have a 50% risk of DVT. [No source is cited for this statistic.]
    • Multiple injuries and lower extremity or pelvic fractures are associated with a higher risk of VTE.
  • Thrombophilia/Thromboembolism History Patients
    • Prior history of DVT/PE confers risk of a future event.
    • As many as 20% of patients with confirmed thromboembolic disease have a history of DVT or PE.
    • Patients with an acquired or genetic predisposition to hypercoagulable states are at risk for VTE. 
If you find yourself among those at highest risk of developing a blood clot and you you are hospitalized, ask your doctor and nurse what precautions they are going to take to prevent you from developing blood clots.  The options for prevention include tight white stockings on the legs (TED hose) that help improve the circulation; "squeezy" wraps to the lower legs that inflate and deflate via an electric pump (many name brands for this type of equipment); injections of blood thinning medication into the skinfolds of your abdomen (Lovenox or Fragmin); or they may simply suggest "early ambulation"--which means you are up and out of bed quickly, in a chair and walking in the hallways.  If they haven't suggested any of these options, insist that they come up with a plan for you.  This is required by the Joint Commision, the authority that accredits hospitals.

Patients--be concerned about pain and swelling in your legs.  Often a blood clot will first appear in the back of one of the lower legs.  This can occur while you are in the hospital or even a few weeks after you get home.  Also be concerned about any sharp pain in the chest, wheezing breath sounds and frequent moist cough; those signs could suggest a small blood clot has gone to the lungs.


. . . .

Tuesday, May 26, 2009

Case Study: H1N1 Swine Flu, my influenza experience

Is this really a case study? Okay, it's more of a personal accounting of the twelve days in May of 2009 during which I was suffering from severe respiratory influenza related to the H1N1 Swine Flu.  I documented the course of this illness because it was so weird and prolonged.  I decided to post my experience for the benefit of others going through a bout of H1N1 influenza.

Here's a rundown of my recent illness:

Day 1: Thurs. eve., May 14th. I noticed that tell-tale "tickle" in my chest and the urge to cough deeply. My husband the mailman had brought this upper-respiratory virus home earlier in the week. After four days of body aches, rest, and frequent cough, he was finally feeling well. I had planned to go visit my elderly parents for the weekend. With the symptoms beginning, I decided to re-evaluate on Friday morning. I didn't want to take them any germs.

Day 2: Fri. May 15th. Woke up feeling "icky" and immediately postponed visiting my folks. A bad headache, cough, body aches and really sore throat came on gradually through the day until I was officially sick by late afternoon.

Day 3: Sat, May 16th. Full blown sickness all day. My sore throat was severe. The headache escalated with every cough and my over-the-counter meds didn't make a lot of progress against any of the symptoms. Lemonade, Popsicles, and fitful sleep punctuated by strange dreams were the theme of the day. I emailed my supervisor to let her know I needed a substitute for my nursing shift on Tuesday.  The way I felt, it was obvious I wouldn't be well enough to be around either patients or other staff by then. I assured her I'd be able to work my planned Friday shift, however.

Day 4: Sun, May 17th. The second day of "full blown sickness."  I was not feeling at all better this day.  I had no appetite at all, a very "icky" taste in my mouth, terrible sore throat, and a frequent cough with nasty green phlegm. My husband was again a huge help in bringing me fluids . . . I experienced constant muscle aches in the upper arms, thighs, abdomen, lower back, and what felt like spasms of deep bone pain to my left lower leg and right upper thigh. (I didn't have much headache from this day forth, however). By late evening I got out of bed and onto the couch to rest so hubby could sleep without being disturbed by my constant coughing, etc..

Late at night I felt well enough to putter around the kitchen briefly. But I suspected I was feverish and confirmed that with the thermometer. (Fever is nature's way of killing bad germs, so that doesn't frighten me at all by the way. I was hoping this meant the illness was going to peak and resolve). I began to experience chills and was generally just plain sick. I did take a dose of Tylenol (acetaminophen). My fever stayed in the 101-102.5 degree Farenheit range most of the night.

Day 5: Mon., May 18th. My highest temp was 103 degrees Farenheit at 6 am on Monday morning, but fever and chills stayed with me for several days. My cough was bringing up very thick, green phlegm. My plan this day was to call the hospital where I work to speak with the employee health nurse. I wanted her to know about my fever and influenza symptoms.  I also asked if our facility was doing any lab surveillance for flu among the employees. (We were not).

I also phoned my doctor's office to ask if they were interested in a sputum specimen for surveillance. (Again the answer was "no").  The nurse related my symptoms to the doctor, and advised that the doctor wanted to see me in the office based on my symptoms, but lab surveillance for H1N1 was only taking place in hospitalized patients in our community. There were no appointments available with my doctor on this day, and I honestly didn't feel well enough to get out of bed anyway so didn't even consider going to see her. I had my laptop at the bedside and felt well enough to write a blog note about my flu. I felt like a "wuss," because my health is robust, and I'm not used to being so fatigued and achy.

My only moments out of bed on this day were to visit the nearby bathroom. I caught a glimpse of my reflection and noticed my face was a waxy, pale yellow. I thought I looked jaundiced. My tongue was also, alarmingly, VERY PALE. I thought the fever had somehow left me anemic. For a moment I thought about checking the whites of my eyes in the mirror, but the room was too dark and the malaise made the hand mirror seem "too heavy." This was a day of feeling completely ill once again.

Day 6, Tues., May 19th. More of the same. I was again shocked to see how yellow my skin was as I passed the mirror. Once again, I thought about looking at my eyes with the hand mirror to check for icterus--but I simply lacked the energy. There was no noticeable improvement in body aches, sore throat, cough or fatigue. I stayed in bed, and was just up to soak in the tub briefly and use the bathroom. I had my laptop at bedside, but didn't have much interest in anything. Although I was technically "resting," it was difficult to get any satisfying sleep.

In the early evening, one of our cats was acting strange and hurt. It seemed like he'd been stung by a bee. We had no liquid benadryl for him in the house so I reluctantly dressed and went to the local Walgreens drugstore. I planned to grab a paper mask to wear in there, but they didn't have any. Not wanting to infect anyone, I made my purchase very quickly and immediately went home. Of course by then the cat seemed recovered enough not to need the medicine. I returned to bed immediately still feeling quite ill and coughing frequently with the constant sore throat and no appetite.

Day 7, Wed., May 20th. I had a feeling that I would not be able to work on Friday after all. I wasn't well yet--still coughing green stuff constantly. Still with a terrible sore throat. After no fever for two days, I started with chills again in the evening and a low grade temp of 100.5. I thought I'd better see the doctor the next day, just to get a note for work so they wouldn't think I was "playing possum."

Day 8, Thurs., May 21st. I was the patient in a mask at the doctor's office.  (Well, I did see one other patient in a mask). The doctor was surprised how sick I was.  She immediately acknowledged influenza and she also suspected possible pneumonia as a consequence.

New symptoms had also developed over the past 24 hours--my left eye was draining green pus. My temp was still hovering in the low 100's. My neck glands were swollen and tender. At the doctor's office I had a chest xray, throat culture and blood work. I told the doctor I felt 70% of normal--so much improved from earlier in the week. Still, the sore throat, cough, and malaise were lingering . . . I was prescribed antibiotic drops to instill in the infected eye.

I immediately returned home to rest. My husband kindly went to get the prescribed eye drops at the pharmacy, and while there he bought me a teddy bear. That's how pathetic I was--sick enough that my husband felt a teddy bear was in order . . .

Reluctantly, I had to notify my hospital yet again that due to this lingering illness I would have to cancel my next scheduled shift (on Sunday).

Day 9, Fri., May 22nd. My doctor called in the morning to give me some results. The chest xray hadn't been read yet by the radiologist, but the lab proved there was no bacterial infection in my throat. The unusual finding was in my blood work. My liver enzymes were alarmingly elevated suggesting that the influenza virus had battled with my liver and caused an acute hepatitis earlier in the week. My shocking yellow color on Monday and Tuesday was, indeed, jaundice.

I was actually feeling better this day . . . so much so that I decided to sanitize certain parts of the house. I focused on disinfecting my kitchen/dining area which included a thorough mopping of the floor and scrubbing of the sink, refrigerator, counters, and trash can. I vacuumed my living room including the crevices of the couch & chairs, did loads of laundry, changed all the sheets, and threw open the doors and windows to get fresh air in and germs out. I even cooked my son a light supper, but was totally spent from the activity before my husband made it home from work.

Overdoing it during that burst of energy really exhausted me. I took a 5-hour-nap on the couch before going to bed for a night's sleep.

Day 10, Sat., May 23rd. Because I had felt improved on Friday, I was optimistic that I'd be able to have a normal day. Instead I was once again very fatigued and my abdomen was very sore in the round ligaments from the constant deep productive cough. I mostly rested to make up from overdoing the house cleaning on Friday.

Day 11, Sun., May 24th. This was a day of actually feeling better for a change. As it was Memorial Day weekend, I wanted to take advantage of a sale at the nearby Bergners store. I drove over, purchased my items, and came home. The air was so fresh, I spent time in our yard, checking my flowers and vegetable plants. The herbs smelled so good, it was inspiring. I got out some branch cutters and did some pruning.

Once again, I later found that that trying to resume my usual level of activity was taxing enough to exhaust me into a long nap. When I woke up hours later, I was suffering from positional vertigo. I've had this vertigo (in which it feels as if the room is spinning when I turn my head) occasionally in the past, but it's always rather disconcerting.

Day 12, Mon., May 25th. The sore throat was almost gone. My eye was better. I still had positional vertigo. The cough was what I call "moist"; it was nagging in spasms that interfered with sleep, but not bringing up as much phlegm. My need for napping was ridiculously high, catching up on a sleep deficit from the illness, I am sure. I still had occasional body aches and pains related to the flu (including the deep "bone pain" in my right thigh that actually persisted on and off for months after this illness!) My appetite was not back and the "sickish-taste" was still there. But, I felt like I was 93% back to normal. Fortunately, I had no scheduled days of work this week.

Day 13, Tues., May 26th. My most lingering symptom was still the cough and a vague, generalized pain in my chest, a constant presence over the past week or so that was annoying but not unbearable. I still had positional vertigo, but my energy and enthusiasm started to return and I was feeling interested enough to write for a while. I planned to call my doctor to see what the xray result showed. I was keenly aware by this point as to what an unusually peristent illness this had become. Because the symptoms had waxed and waned so much, I wasn't even confident at this point that I was truly over it yet. (I am certain that I've never been affected by an illness for so long in my adult life).

Follow up: My chest xray was negative for pneumonia. A week after the first blood tests, my liver enzymes had returned to normal. I was still coughing "mildly" and bringing up (by then) clear phlegm into the first week of June when my son graduated from high school. By the second week of June, I was completely well, except:  my job requires a great deal of physical exertion and I must say that when I returned to work, I noted a distinct loss of stamina after my illness with the H1N1 Swine Flu.

My H1N1 Phlegm:  I took this phlegm photo at the end of my May 2009 bout with H1N1 Swine Flu.  I was feeling quite a bit better at the time, but still effortlessly coughing wads of disgusting phlegm.  I know it's gross . . . my lungs were full of this stuff, and it was much worse earlier in the illness before I had enough energy to document it.

Search terms that bring traffic to this blog post.  As of March 2010 my search log continues to show me that this is my most-read blog entry.  People most frequently use search terms that include "lingering cough," "yellow (or) green phlegm," "H1N1 with vertigo," and "H1N1 with jaundice (or) elevated liver enzymes."  (Importantly, I periodically also see search terms that suggest individuals have developed jaundice after receiving the vaccine against H1N1).

You might find these relevant articles of interest:

This page from the CDC website explains when it is recommended to collect specimens for H1N1 surveillance. Obviously we want to have an idea of how much influenza is out there, where it is located, and the emerging patterns of the illness. At the same time, it's unwise to test everyone, everywhere for the illness. We'd be expending resources at a cost that doesn't give us any benefit. Influenza as a general diagnosis can be made based on symptoms. Antibiotics are not a treatment for viral illnesses like influenza, and anti-viral medications are not frequently used either. This is one of those illnesses that requires our immune system to fight the virus.

Here is a 2006 article explaining a relationship between Influenza and a bout of acute hepatitis: Systemic Viral Infections and Collateral Damage in the Liver by David H. Adams and Stefan G. Hubscher. (American Journal of Pathology. 2006;168:1057-1059.) See paragraph 2, Understanding Hepatitis in Influenza.

Want to review the basics about influenza?  Here's a link to my general information about the flu.
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Saturday, January 10, 2009

MRSA: Healthcare vs. Community Acquired

Where did it come from?!!

In the last few years, Methacillin-resistant Staphylococcus Aureus (MRSA) has gotten just a bit more complicated. Now it is common for physicians to attempt to make a distinction as to how the infection was acquired. While the healthcare setting (hospitals and nursing homes in particular) have long been known to harbor Super Bugs like MRSA, this infection is now showing up in the community at large.

Healthcare-Associated MRSA is also called "healthcare acquired" and HA-MRSA. Super Bugs like MRSA live in the hospital setting for a lot of good reasons. There are plenty of vulnerable individuals--often with weakend immune systems--for the germs to infect. Patients with bacterial infections are routinely treated with strong antibiotics while in-hospital. But, not every germ is killed with the first dose of an antibiotic. That's why antibiotics are continued over a designated period of time--so that the reproducing generations of bacteria can be targeted at regular intervals until they are all gone. Meanwhile, some of the bacteria that survived the initial doses of antibiotics will be shed from the infected patient through body secretions (like mucus, urine, etc.) The bacteria that have survived have learned a thing or two from their near-fatal antibiotic exposure.  They learned ways to dodge the effects of that antibiotic, and these bacteria are ready to reproduce into entire colonies of "strong bacteria" once they find a "host" to infect. The bacteria live on hard surfaces and can be easily passed from person to person. Patients with catheters in their bladders, breathing tubes, central IV lines, and fresh surgical incisions are particularly vulnerable to bacteria "walking in" to their bladder, airway, bloodstream, or wound if proper hygiene is not meticulously attended to. (When patients acquire an infection in the hospital setting--one that they didn't come in with--any infection, not just MRSA--it is called a nosocomial infection.)


Community-Associated MRSA: Also called "community-acquired" or CA-MRSA. MRSA that infects individuals who have not been hospitalized within the past a year and who haven't had a recent medical procedure is described as community-associated. CA-MRSA frequently causes skin infections like boils, pimples, or abcesses. Some patients initially mistake these skin lesions as a spider bite. (It's important to be skeptical of the spider bite theory and have any suspicious boils examined and treated.) CA-MRSA has resulted in outbreaks of skin infections among atheletes who share equipment and personal items.


Here is an excerpt of the CDC's guidelines for cleaning and disinfecting to reduce transmission of CA-MRSA:

"What can I do to keep surfaces free from staph and MRSA?
  • Cover your infections. Covering infections with bandages or dressings is the best way to keep surfaces from becoming contaminated with staph and MRSA.
  • Clean your hands often. Wash your hands often with soap and water or use an alcohol-based hand rub when a sink is not available. Always clean your hands after changing bandages or touching infected skin.
  • Keep the environment clean. Regularly clean frequently touched surfaces and other items that come into direct contact with infected skin.
  • In gyms, locker rooms, and other places where many people come and go, repair or throw out equipment and furniture with damaged surfaces that cannot be thoroughly cleaned.
What surfaces should be the focus of my cleaning efforts?Focus on surfaces that touch people’s bare skin each day and any surfaces that could come into contact with uncovered infections. For example, surfaces such as benches and equipment in the weight room or locker room. Large surfaces, such as floors and walls, have not been directly involved in the spread of staph and MRSA . . .

Which disinfectants should I use against staph and MRSA?Disinfectants effective against Staphylococcus aureus or staph are most likely also effective against MRSA. These products are readily available from grocery stores and other retail stores . . . Most, if not all, disinfectant manufacturers will provide a list of germs on their label that their product can destroy . . .

How do I know if the surfaces or equipment are properly cleaned?Although in most situations you will not know if a surface has been cleaned, it’s important to remember that most surfaces do not pose a risk of spreading staph and MRSA. If cleaning procedures are unknown, taking the appropriate precautions such as:
  • Using barriers like a towel or clothing between your skin and the surface.
  • Showering immediately after activities where you have direct skin contact with people or shared surfaces such as after exercising at a health club.
  • Cleaning your hands regularly.
  • Keeping cuts and scrapes clean and covered with bandages or dressing until healed.
    These precautions are especially important in settings such as in locker rooms, gyms, and health clubs.
How should shared equipment like sports gear be cleaned?Shared equipment that comes into direct skin contact should be cleaned after each use and allowed to dry. Equipment, such as helmets and protective gear, should be cleaned according to the equipment manufacturers’ instructions to make sure the cleaner will not harm the item.

Will routine laundry processes, detergents, and laundry additives remove staph and MRSA from towels, clothes, linens, and uniforms?Yes. Routine laundry procedures, detergents, and laundry additives will all help to make clothes, towels, and linens safe to wear or touch. If items have been contaminated by infectious material, these may be laundered separately, but this is not absolutely necessary."

Visit the CDC's MRSA site for an abundance of information on community and hospital-acquired infection.

Just in case I forget to post it elsewhere--a few more words of advice from me:
  • don't share towels and washcloths (period)
  • don't share razors--and replace your razor or blade if you have had a recent skin infection